Exercise may influence components of executive functioning, specifically cognitive control and action monitoring. We aimed to determine whether high level exercise improves the efficacy of cognitive control in response to differing levels of conflict. Fitter individuals were expected to demonstrate enhanced action monitoring and optimal levels of cognitive control in response to changing task demands. Participants were divided into the highly active or low-active group based on self-reported activity using the International Physical Activity Questionnaire. A modified flanker task was then (...) performed, in which the level of conflict was modulated by distance of distractors from the target and congruency of arrows. Electroencephalography was collected during 800 trials; trials were 80% congruent, 20% incongruent, 50% close, and 50% far. The error-related negativity and error positivity were extracted from the difference wave of correct and incorrect response locked epochs, the N2 from the difference wave of congruent and incongruent stimulus locked epochs and the P3 from stimulus locked epochs. The HA group showed a larger Pe amplitude compared to the low-active group. Close trials elicited a larger N2 amplitude than far trials in the HA group, but not the low-active group, the HA group also made fewer errors on far trials than on close trials. Finally, the P3 was smaller in the lowest conflict condition in the HA, but not the low-active group. These findings suggest that habitual, high levels of exercise may influence the endogenous processing involved in pre-response conflict detection and the post-error response. (shrink)

When testing primates with cognitive tasks, it is usually not considered that subjects differ markedly in terms of emotional reactivity toward the experimenter, which potentially affects a subject’s cognitive performance. We addressed this issue in common marmosets (Callithrix jacchus), a monkey species in which males tend to show stronger emotional reactivity in testing situations, whereas females have been reported to outperform males in cognitive tasks. In a two-phase experiment, we first quantified the emotional reactivity of 14 subjects toward four different (...) experimenters performing a standardized behavioral action sequence and then assessed whether and how it affected the subjects’ participation and performance in a subsequent object permanence task. A test session was terminated if a subject refused to make a choice in four consecutive trials. Highly emotionally aroused individuals, particularly males, were less likely to participate in the cognitive task and completed fewer trials. However, whenever they did participate and were attentive to the task, their performance was not affected. Our results suggest that differences in emotional reactivity toward an experimenter have no major impact on cognitive performance if strict criteria are applied on when to abandon a test session and if performance is corrected for attention to the test procedure. Furthermore, they suggest that the reported sex differences in cognitive performance in marmosets may be owing to motivational and attentional factors, rather than a difference in cognitive ability per se. (shrink)

The 2017–2018 basic income pilot in the Canadian province of Ontario attempted to alleviate poverty in a precarious economy. With three communities participating, we examine how the pilot was framed by local media, permitting a look at the narratives that were dominant in the participating communities. In essence, were recipients framed as “deserving?” How the media addresses this question can set the foundation for whether policymakers can proceed with basic income. Given that media coverage of poverty alleviation in the United (...) States generally follows an episodic frame, which puts focus on individuals and their particular circumstances (i.e. lifestyle choices), while major Canadian media generally shows a mix of frames, results of a media content analysis at the local level shows basic-income pilot was covered mainly through thematic frames, which emphasizes systemic factors and more general social conditions, which support state action on basic income. (shrink)

RésuméFerdinand de Saussure postule une science générale des signes qu’il ap-pelle sémiologie. La langue n’en serait qu’un cas particulier caractériée par l’arbitrariété totale de ses unités. Cette caractéristique reviendrait aussi à l’écriture qui n’est cependant pas un systéme sémiologique primaire, mais un système secondaire dont la fonction est de représenter un système pri-maire. Il existe en outre des systèmes tertiaires comme, par example, l’alphabet Morse, l’écriture Braille, les systèmes de chiffrage, etc. Les modes de manifestation peuvent être soit acoustique soit (...) visuel. Tandis que la langue et l’écriture sont totalement arbitraires, les autres systèmes sémiologiques peuvent être motivés jusqu’à un certain de-gré. À côté des sémiologies utilitaires il existe aussi des sémiologies esthé-tiques comme, par example, les légendes. La sémiologie elle-même n’est qu’un cas particulier de la sémiotique qui tient aussi compte des signes naturels. Les frontières entre langue, sémiologie et et sémiotique sont souvent flottantes et imprécises. (shrink)

Die Frage nach dem Wesen und Wert menschlicher Erkenntnis ist so alt wie die Philosophie selbst. In diesem Band erortern in zwanzig Beitragen namhafte Philosophen und Theologen aus dem In-und Ausland Fragen der Erkenntnistheorie in systematischer wie philosophiehistorischer Perspektive. Zum einen stehen dabei Grundfragen der Erkenntnistheorie im Blickfeld, wie etwa der grundsatzlichen Frage nach Wahrheit und Methode, Erinnerungsvermogen oder dem der Evidenz. Zum anderen erortert ein zweiter Themenkreis spezielle Themen wie dem der Wesenserkenntnis, Analogie und Personalitat. Ein dritter Kreis umfasst (...) Fragen nach der Existenz der Welt und der Bedeutung des Realismus fur die Ethik. Dem anschliessend befassen sich weitere Beitrage mit der Religionsphilosophie, insbesondere der Bedeutung naturlicher Gotteserkenntnis und dem Begriff des Wunders. Zu guter Letzt geht ein letzter Themenkreis auf spezifisch theologische Probleme der Erkenntnislehre ein, die sich in der katholischen Tradition ergeben, wie etwa dem Verhaltnis des Philosophen zu Christus, oder dem Vorherwissen Gottes. (shrink)

How were various strata of local history—Classical, Christian, and Muslim—incorporated into the building of imperial Seville (sixteenth and seventeenth centuries), and what was the impact of the critical approach to evidence developed in Renaissance Italy on actual urban projects? Three case-studies—of a noble palace, the Casa de Pilatos; of a public park, the Alameda de Hércules; and of a carpentry treatise by master builder Diego López de Arenas—reveal the malleable role of historical evidence in monumental construction projects based on classical (...) and Christian ideals and demonstrate a more methodical use of evidence among artisans practicing traditional medieval craftsmanship. (shrink)

ABSTRACT:Suicide is a worldwide public health issue, and suicide ideation and behavior among adolescents, females in particular, have been increasing. Focusing on the risk factors that are unique to adolescents and adolescent females can help tailor and inform prevention strategies. There are unique biological, psychological, social, and societal factors that contribute to suicide ideation and behavior among adolescent females. Some of these include hormonal fluctuations and sensitivity, developing brain systems, impacts of social media, maladaptive coping, and peer influence. These changes (...) do not occur in a vacuum and have recently been impacted by the COVID-19 pandemic, which has been associated with increased social isolation and decreased mental health. By identifying how these factors coalesce and interact to drive suicide ideation and behavior, we can derive potential solutions to this problem. Given the variability in individuals, families, and communities, and the interacting and reinforcing nature of these risk factors, a multi-pronged approach that incorporates multiple interventions and involves families, schools, and communities is needed. (shrink)

Metaphors used to describe new technologies mediate public understanding of the innovations. Analyzing the linguistic, rhetorical, and affective aspects of these metaphors opens the range of issues available for bioethical scrutiny and increases public accountability. This article shows how such a multidisciplinary approach can be useful by looking at a set of texts about one issue, the use of a newly developed technique for genetic modification, CRISPRcas9.

To assess the effectiveness of Visual Thinking Strategies in medical education curricula, a pretest–posttest experimental study design was used to evaluate the impact of participating in VTS workshops on first-year medical students. A total of forty-one intervention and sixty comparative students completed the study which included the analysis of clinical images followed by a measurement of word count, length of time analyzing images, and quality of written observations of clinical images. VTS training increased the total number of words used to (...) describe clinical images, the time spent analyzing the images, and the number of clinically relevant observations. (shrink)

In his recently published Where the Conflict Really Lies: Science, Religion, & Naturalism 2011 Alvin Plantinga criticises Paul Draper’s evolutionary argument against theism as part of a larger project to show that evolution poses no threat to Christian belief. Plantinga focuses upon Draper’s probabilistic claim that the facts of evolution are much more probable on naturalism than on theism, and with regard to that claim makes two specific points. First, Draper’s probabilistic claim contradicts theism’s necessary falsehood; unless Draper wishes to (...) acknowledge that theism is necessarily true, his claim commits him to theism’s contingency and so sets him at odds with a mainstream that sees God’s existence as decidedly noncontingent. Second, Plantinga argues that Draper’s probabilistic claim is, even if true, overwhelmed by counterclaims about facts that are more likely on theism than naturalism. I argue this critique of Draper depends upon a serious error, and that Plantinga overlooks the full implications of his own presuppositions. Correcting these shortcomings shows that Plantinga’s own probabilistic-apologetics (e.g., the ‘Evolutionary Argument Against Naturalism’) requires theism’s contingency no less than does Draper’s atheology. (shrink)

Mimesis as Make-Believe is important reading for everyone interested in the workings of representational art.

Although critical reception of discourse markers (DMs) such as like and you know has often been noted, surprisingly little research has actually investigated this attitudinal perspective on usage. Moreover, a recent, rapidly expanding body of research on non-L1 speakers’ use of discourse markers in English has suggested that their more or less frequent use of specific markers may be due to familiarity with these markers and positive or negative marker perceptions. The present study presents the results of a survey measuring (...) British English L1 speakers’, English as Foreign Language (EFL) learners’, and English as a Lingua Franca (ELF) speakers’ perceptions of the discourse markers so, like, well and you know and their reactions to either abundance or lack of DMs. The survey measured speaker attitudes by asking participants to evaluate the usage of other DMs. We found that L1, EFL, and ELF have varying attitudes about certain markers, and these markers are perceived differently for traits like politeness and friendliness. Generally speaking, L1 speakers were more positively disposed towards markers than either of the other groups, who in their turn rated the propositional functions of the markers as more acceptable than interactional functions. (shrink)

Deep brain stimulation of the subthalamic nucleus is an effective treatment for the motor symptoms of movement disorders including Parkinson's Disease. Despite its therapeutic benefits, STN-DBS has been associated with adverse effects on mood and cognition. Specifically, apathy, which is defined as a loss of motivation, has been reported to emerge or to worsen following STN-DBS. However, it is often challenging to disentangle the effects of STN-DBSper sefrom concurrent reduction of dopamine replacement therapy, from underlying PD pathology or from disease (...) progression. To this end, pre-clinical models allow for the dissociation of each of these factors, and to establish neural substrates underlying the emergence of motivational symptoms following STN-DBS. Here, we performed a systematic analysis of rodent studies assessing the effects of STN-DBS on reward seeking, reward motivation and reward consumption across a variety of behavioral paradigms. We find that STN-DBS decreases reward seeking in the majority of experiments, and we outline how design of the behavioral task and DBS parameters can influence experimental outcomes. While an early hypothesis posited that DBS acts as a “functional lesion,” an analysis of lesions and inhibition of the STN revealed no consistent pattern on reward-related behavior. Thus, we discuss alternative mechanisms that could contribute to the amotivational effects of STN-DBS. We also argue that optogenetic-assisted circuit dissection could yield important insight into the effects of the STN on motivated behavior in health and disease. Understanding the mechanisms underlying the effects of STN-DBS on motivated behavior-will be critical for optimizing the clinical application of STN-DBS. (shrink)

ZusammenfassungDer Selbstbestimmungdes Patienten kommt in der modernen Debatte über das Gesundheitswesen eine zentrale Bedeutung zu. Selbstbestimmung ist aber ein voraussetzungsvoller Begriff, der für Patientengruppen wie Demenzbetroffene, deren Entscheidungs- und Einwilligungsfähigkeit nachlässt oder nicht mehr gegeben ist, eine Reihe von Fragen aufwirft. Auf der Grundlage der jeweiligen Symptomentwicklung der Demenzerkrankung und eigener Erfahrungen im Umgang mit Demenzbetroffenen wirdde rEntwicklungdes Willens in den verschiedenen Stadien der Demenz nachgegangen. Dabei wird den Dimensionen der Differenziertheit der Denkinhalte, der Beurteilungsbasis und der Entscheidungskonstanz eine besondere (...) Bedeutung zugemessen und für eine Graduierung der Selbstbestimmungsmöglichkeiten im Umgang mit Demenzbetroffenen plädiert. Wegen der Schwererkennbarkeit der oft verschlüsselten Willensbekundungen Demenzbetroffener wird der Willenswahrnehmung und dem Training der genauen Beobachtung, Einfühlung und Sensibilität im Umgang mit den Betroffenen großes Gewicht beigemessen. Als Ziel wird die jeweils weitestgehende Selbstbestimmung, im Verlaufe der Erkrankung auch Teilselbstbestimmung und schließlich Mitwirkung bei der individuellen Wohlbestimmung im Sinne eines Grundrechtsschutzes vertreten. (shrink)

The penultimate chapter of Alvin Plantinga's "Warrant and Proper Function" attacks metaphysical naturalism through an argument which concludes that only a supernaturalistic worldview can accommodate the indispensable concept of proper function. I make the case that this argument, which I dub 'the argument from proper function', suffers from two major flaws. First, it underestimates the naturalist's ability to ground natural proper function ascriptions in the concept of health. Second, it relies upon an overly stringent standard for successful conceptual analysis; ironically, (...) the naturalist can undercut the argument by adopting Plantinga's own recommended model for analysing concepts. (shrink)

ZusammenfassungDer Selbstbestimmungdes Patienten kommt in der modernen Debatte über das Gesundheitswesen eine zentrale Bedeutung zu. Selbstbestimmung ist aber ein voraussetzungsvoller Begriff, der für Patientengruppen wie Demenzbetroffene, deren Entscheidungs- und Einwilligungsfähigkeit nachlässt oder nicht mehr gegeben ist, eine Reihe von Fragen aufwirft. Auf der Grundlage der jeweiligen Symptomentwicklung der Demenzerkrankung und eigener Erfahrungen im Umgang mit Demenzbetroffenen wirdde rEntwicklungdes Willens in den verschiedenen Stadien der Demenz nachgegangen. Dabei wird den Dimensionen der Differenziertheit der Denkinhalte, der Beurteilungsbasis und der Entscheidungskonstanz eine besondere (...) Bedeutung zugemessen und für eine Graduierung der Selbstbestimmungsmöglichkeiten im Umgang mit Demenzbetroffenen plädiert. Wegen der Schwererkennbarkeit der oft verschlüsselten Willensbekundungen Demenzbetroffener wird der Willenswahrnehmung und dem Training der genauen Beobachtung, Einfühlung und Sensibilität im Umgang mit den Betroffenen großes Gewicht beigemessen. Als Ziel wird die jeweils weitestgehende Selbstbestimmung, im Verlaufe der Erkrankung auch Teilselbstbestimmung und schließlich Mitwirkung bei der individuellen Wohlbestimmung im Sinne eines Grundrechtsschutzes vertreten. (shrink)

Der Selbstbestimmungdes Patienten kommt in der modernen Debatte über das Gesundheitswesen eine zentrale Bedeutung zu. Selbstbestimmung ist aber ein voraussetzungsvoller Begriff, der für Patientengruppen wie Demenzbetroffene, deren Entscheidungs- und Einwilligungsfähigkeit nachlässt oder nicht mehr gegeben ist, eine Reihe von Fragen aufwirft. Auf der Grundlage der jeweiligen Symptomentwicklung der Demenzerkrankung und eigener Erfahrungen im Umgang mit Demenzbetroffenen wirdde rEntwicklungdes Willens in den verschiedenen Stadien der Demenz nachgegangen. Dabei wird den Dimensionen der Differenziertheit der Denkinhalte, der Beurteilungsbasis und der Entscheidungskonstanz eine besondere (...) Bedeutung zugemessen und für eine Graduierung der Selbstbestimmungsmöglichkeiten im Umgang mit Demenzbetroffenen plädiert. Wegen der Schwererkennbarkeit der oft verschlüsselten Willensbekundungen Demenzbetroffener wird der Willenswahrnehmung und dem Training der genauen Beobachtung, Einfühlung und Sensibilität im Umgang mit den Betroffenen großes Gewicht beigemessen. Als Ziel wird die jeweils weitestgehende Selbstbestimmung, im Verlaufe der Erkrankung auch Teilselbstbestimmung und schließlich Mitwirkung bei der individuellen Wohlbestimmung im Sinne eines Grundrechtsschutzes vertreten. (shrink)

Alvin Plantinga’s Warranted Christian Belief (2000) is the capstone to the latest stage in his views on the intellectual credibility of theism in general, and Christian theism in particular. While Plantinga’s stature in the community of Christian philosophers alone makes gaining familiarity with this text a good idea for contemporary analytic philosophers of religion, its vigorous, innovative defense of specifically Christian theism and daring suggestions for renovating the landscape of analytic philosophy of religion merit serious consideration. I aim to provide (...) a useful introduction to the book’s contents and critique some of its main claims. (shrink)